The enteric nervous system (ENS), the largest division of autonomic nervous system, is a tantalizing frontier in neuroscience. With the advent of single-cell transcriptomics, the ENS has been ...

The study will interest researchers studying genome organisation in mitosis. Genomes assume a complex 3D architecture in the interphase cell nucleus. Yet, the molecular mechanisms that determine ...

More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, ...

The paper emphasizes that AI achieves "superhuman performance" by actively retrieving and integrating complex external ...

Shenzhen Science and Technology Serial Funds (Guangdong, China) (No. GJHZ20210705141400002, KCXFZ20211020164543006, ...

Prostate cancer (PCa) is one of the most common malignant tumors in men worldwide. While early detection has improved patient ...

视网膜母细胞瘤蛋白（pRb）及其下游效应子E2F转录因子家族共同构成的RB1/E2F信号轴，是细胞命运和增殖的核心调控中枢。该轴的经典功能是作为细胞周期从G1期向S期过渡的关键“门卫”，确保细胞在适当的条件下才进行DNA复制。然而，其生物学意义远不止 ...

The study by Reed et al. provides fundamental findings and convincing evidence defining the topological changes that occur during tumorigenesis. The findings enhance the understanding of stable ...