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H5N1高致病性禽流感跨物种传播至奶牛:新型基因型B3.13与D1.1的流行 ...
本文聚焦2024-2025年美国爆发的2.3.4.4b分支HPAI H5N1新型基因型B3.13和D1.1,首次揭示其通过野鸟迁徙传入并跨物种感染奶牛,引发乳腺炎和产奶量骤降。研究通过基因组溯源发现两类基因型均为"4+4"重配株(B3.13保留欧亚谱系A1的PA/HA/NA/M基因,D1.1保留A3的PB1/HA/M/NS基因),证实PB2 ...
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