Helicases and nucleic acid translocases are motor proteins that have essential roles in nearly all aspects of nucleic acid metabolism, ranging from DNA replication to chromatin remodelling.

Paradoxically, a tumor suppressor role of VGLL3 was also reported in ... be recruited to DSBs in a PARylation- and ...

Building on these findings, the team further investigated the role of PICH in ... (TOP2A), in untangling the DNA threads. Second, it works with a protein called BLM helicase to convert tangled ...

The research uncovers the vital role of a protein called ... IIα (TOP2A), in untangling the DNA threads. Second, it works with a protein called BLM helicase to convert tangled threads into ...