The hairpin ribozyme catalyses sequence-specific cleavage of RNA. ... D. M. & Bevilacqua, P. C. General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme. Science 287, 1493 ...

This specific spatial arrangement of aspartic acid, histidine, and serine has been found in hundreds of enzymes and is often referred to as "the catalytic triad" (Blow et al. 1969.) ...

Key To Unlocking The Secret Of Highly Specific DNAzyme Catalysis Discovered. ScienceDaily. Retrieved June 4, 2025 from www.sciencedaily.com / releases / 2007 / 11 / 071112100657.htm.

Researchers from the Chinese Academy of Sciences (CAS) and their collaborators at Qi Biodesign have developed a strand-specific, CRISPR-free editing system for modifying genomes in the nucleus ...

Metagenomi Adenine Base Editors (ABEs) demonstrated over 95% genome targetability Simultaneous ABE triplex editing resulted in over 95% protein knockdown in primary T-cells ABE demonstrated highly ...

Base editing is a precise genome editing technology that enables the direct conversion of one base pair to another without inducing double-strand breaks (DSBs) in the DNA.Unlike conventional genome ...

Upon examining the catalyst further, the team found its specific surface area (46 m 2 /g) to be 10 times higher than those of commercially available titanates (1–4 m 2 /g). Prof.

By fusing a nickase Cas9 with ssDNA-specific deaminases, they have successively developed the cytosine base editor (CBE) and adenine base editor (ABE) systems, which allow efficient C·G-to-T·A ...