Sitosterolemia is a rare, recessively inherited lipid disorder caused by biallelic mutations in genes encoding the ATP-binding cassette transporters, ABCG5 and ABCG8. Such genetic defects lead to ...

A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...

Phytosterols not only support plant development but also offer health benefits such as cholesterol-lowering, anti-inflammatory, and anticancer properties. Rapeseed oil, rich in phytosterols like ...

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism. Bile acids are natural ligands of FXR, which bind to the ...