An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Sr incorporation in PEEK via a polydopamine coating improves osteogenic potential, promoting cell adhesion and mineralization for orthopedic applications.

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially life- ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, ...

Evasion of cell death is a hallmark of cancer cells that enables them to overcome endogenous barriers to cancer development ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Copyright: © 2025 Elsevier Ltd. Published by Elsevier Ltd. CAR T-cell therapies have revolutionised treatment of many diseases, but their expense means many patients ...

Solid lines are stimulation and dashed lines are inhibition. NK, natural-killer cells; MO, macrophage; Th1, T- helper lymphocyte type 1 cells; Th2, T-helper lymphocyte type 2 cells; TNF, tumour ...

On day 6, cells were harvested for flow cytometry staining and analysis. For the proliferation assay of murine CD8+ T cells, single peptide and repeat peptide stimulated cells were cultured from day 0 ...

prevent dysfunction and increase T cell proliferation. We also found that inhibition or deletion of TBK1 made cancer cells more susceptible to immune cell targeting and destruction. The findings ...