Furthermore, wound healing and Transwell assay elucidated the higher antimigration effect of ternary nanocomplex than DOX-Duplex or miR-34a delivery. Overall, the combinatorial delivery of DOX and miR ...

While it is accepted that extracellular vesicles (EVs)-mediated transfer of microRNAs contributes to intercellular communication, the knowledge about molecular mechanisms controlling the selective and ...

Idaho National Lab partners with Clean Core to test a new thorium-based nuclear fuel that may improve safety, cut waste, and ...

During early drug development and preclinical development, researchers use in vitro cultured lymphocytes to induce cytokine ...

The cell NAD+/NADH ratio can constrain biomass synthesis and influence proliferation in nutrient-limited environments. However, which cell processes regulate the NAD+/NADH ratio is not known. Here, we ...

The T-cell proliferation assay identified a downregulation of anti-donor responses of CD4 (P =.032) and CD8 (P =.016) T cells at 12 months in the intervention cohort compared with the control group.

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can offer new treatment opportunities.

Nova Pacific Metals Corp. is pleased to report assays from the first four holes, totaling 582 metres , of its ongoing 8,700-m exploration drilling campaign at the Coronation area of its Lara VMS ...

SR9009 was found to exert REV-ERB–independent effects on proliferation, metabolism, and gene transcription in 2 different cell types depleted of REV-ERBs. Therefore, effects of these drugs cannot be ...

CAR T-cell therapy as option for diseases of the peripheral nervous system Our work shows that the targeted use of CAR T-cells is possible and of significant clinical benefit, even for severe ...

T Cell Proliferation Assay T cell proliferation was assessed using CFSE staining, a commonly used method to monitor cell division by measuring dye dilution over multiple generations.