Summary Human Health Risk Assessments (HHRAs) are a key aspect of the toxicology toolbox and apply to multiple industries be it tobacco, pharmaceutical, food or cosmetics, and are also a key part of ...

This work demonstrates that protective safety decisions can be made for DART without generating new animal test data. Keywords: New approach methodologies, Risk Assessment, Developmental and ...

The fresh energy brought by the revitalized research attention offers an opportunity to more closely integrate novel drug discovery, residue monitoring, and ...

Toxicology is the scientific discipline concerned with the detection, evaluation and prevention of the toxic effects of substances that humans are exposed to. It has a key role in the development ...

Heart disease remains a significant human health burden worldwide with a significant fraction of morbidity attributable to environmental exposures. However, the extent to which the thousands of ...

Connecticut is among several states that uses the herbicide Diquat to combat hydrilla, an invasive plant species that grows ...

Introduction Hospital-acquired thrombosis accounts for a large proportion of all venous thromboembolism (VTE), with significant morbidity and mortality. This subset of VTE can be reduced through ...

A recent report raised concerns that it contains high levels of the heavy metal. Here’s what that may mean for your health.

Shampoo chemicals called polyquaterniums stick to tiny aquatic animals. They slow swimming and feeding, risking ecosystems ...

Idiosyncratic adverse drug reactions (IADRs) in humans can result in a broad range of clinically significant toxicities leading to attrition during drug development as well as postlicensing withdrawal ...