Instead of fixing one of the many genes that can be mutated, the technique addresses a type of mutation they share, a stop codon that cuts off protein production too soon.

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Enter tRNA. "Transfer RNAs are ancient molecules," said Gustavo Caetano-Anollés of the University of Illinois at Urbana-Champaign. "They're molecular fossils." Caetano-Anollés and his colleague ...

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of ...

Transfer RNA, more commonly referred to as tRNA, is well known for its key role in translating genetic material into protein. Recent discoveries about fragments of tRNA, which scientists had ...

James Chappell, associate professor of biosciences and bioengineering at Rice University. In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, ...

Replicate Bioscience, a clinical-stage company pioneering novel self-replicating RNA (srRNA) technology for applications across infectious disease, immunology, and other therapeutic areas, and ...

Initially dismissed as a wealthy and frivolous socialite, Charles Swann in Marcel Proust’s “In Search of Lost Time” eventually transforms from a minor figure to an important one. Were biology a novel, ...