tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

Professor Zhou's research group focuses on developing and applying new technologies to visualize spatial and temporal distributions of chemical modifications in the mammalian transcriptome at ...

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

Study reveals how an RNA enzyme drives the postnatal switch from glucose to fatty acids in heart cells, highlighting ketogenesis as essential for metabolism. Study: The tRNA methyltransferase Mettl1 ...

James Chappell, associate professor of biosciences and bioengineering at Rice University. In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, ...