Transition-state theory has provided the theoretical framework to explain the enormous rate accelerations of chemical reactions by enzymes. Given that proteins display large ensembles of conformations ...

Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130023, P. R. China ...

To continue with catalysis in cofactor-independent oxygenases, the caged radicals recombine to form a peroxide intermediate. After these common steps, the peroxide or hydroperoxide can react in ...

A synthetic hydrolase enzyme with activity comparable to natural proteins has been designed from scratch using a combination of generative AI techniques. Synthetic proteins that promote multi-step ...

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells ...

A research team, led by Professor Dong Woog Lee from the Department of Chemistry at UNIST, in collaboration with Professor ...

Catalysis is fundamental to creating materials ... Most of the stuff we do, nature did it before.” “What's an enzyme? A protein. We have enzymes for many different reactions, the purpose ...

Evonik Oxeno GmbH & Co. KG, Paul-Baumann-Str. 1, Marl 45772, Germany ...