Alan Herbert, InsideOutBio, discusses the significant advancements in RNA therapeutics, highlighting their role in supporting ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the ...

New tool classifies cell types from single-cell RNA sequencing data with speed and accuracy, processing 650k cells in 6 ...

Ion-pairing reversed-phase liquid chromatography (IP-RPLC), a standard method to characterize small oligonucleotides, can also separate large RNA molecules. Its advantages extend beyond simple ...

This study illustrates a valuable application of BID-seq to bacterial RNA, allowing transcriptome-wide mapping of pseudouridine modifications across various bacterial species. The evidence presented ...

A study from Würzburg reveals that pox viruses have developed a unique strategy to rapidly multiply after infecting a host ...

A group of Australian scientists has uncovered a new way to fight some of the toughest cancers by targeting an overlooked cellular process called minor splicing. This tiny but vital mechanism turns ...

A CRISPR system detects rare cancer mutations in blood with single-nucleotide precision, outperforming ddPCR through ...