Cryo-Electron Microscopy (Cryo-EM) is an approach that allows the observation of hydrated biological specimens in their native environment at cryogenic temperatures in transmission electron microscopy ...

Using technologies like electron microscopy (EM) it is possible to capture molecular mechanisms in great detail, but not when these mechanisms are currently moving. The field of cryomicroscopy circ… ...

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveal their inner structures. It occurs during an essential step of imaging ...

Cryo-ET/EM postdoctoral position immediately available in Zhu Lab at Case Western Reserve University A postdoctoral position is immediately available in the Zhu Lab in the Department of Physiology and ...

The researchers used cryo-EM to study the amyloid fibers formed by hnRNPDL-2, which indicated that they are non-toxic and bind nucleic acids in their aggregated state. The structure of the protein ...

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the 3D structure of biomolecules at near-atomic resolution, revolutionizing structural biology and drug discovery.

Okinawa Institute of Science and Technology (OIST) Graduate University researchers have uncovered the atomic structure of the “APOBEC3G-Vif complex” using cryo-electron microscopy. Their ...

Cryo-electron microscopy (cryo-EM) has advanced rapidly in the past few years, positioning itself as an invaluable tool for the pharmaceutical industry. Nobel Laureate Richard Henderson predicted ...

New cryo-EM images shed light on Wnt signaling Atomic-resolution pictures could eventually lead to better cancer drugs, researchers say Date: August 16, 2022 Source: UT Southwestern Medical Center ...

Additionally, cryo-EM is transforming cellular and structural biology by allowing researchers to observe the structure of proteins and biomolecular complexes in-situ within cells and tissue.

Researchers have used cryo-EM to capture the structure of MCM8/9, a protein complex implicated in infertility and cancer.