Structure of the poxviral core protein A10. The three subunits of the trimer (colored differently) are represented as simulated cryo-EM surfaces in front of a raw cryo-EM micrograph. The cryo-EM ...

WEST LAFAYETTE, Ind. — Purdue University experts in the College of Science and Rosen Center for Advanced Computing have launched Molecular Intelligence, a software company whose solutions help ...

Information about macromolecular structure of protein complexes and related cellular and molecular mechanisms can assist the search for vaccines and drug development processes. To obtain such ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

Glutamate-gated AMPA receptors mediate the fast component of excitatory signal transduction at chemical synapses throughout all regions of the mammalian brain. AMPA receptors are tetrameric assemblies ...

Researchers at the VIB-VUB Center for Structural Biology have developed a new microfluidics-based workflow that enables high-resolution cryogenic electron microscopy (cryo-EM) structure determination ...

Generate Biomedicines, which uses artificial intelligence for protein design, recently opened a cryo-electron microscopy (cryo-EM) laboratory in Andover, Massachusetts, that it says will accelerate ...

Particles (encircled in green) are spaced at a distance from the noise surrounding the nanobeads (purple), which would otherwise obscure them. Sample loss has been a persistent problem in cryo-EM, a ...

The Cryo-Electron Microscopy Facility (CEMF) advances the overall UAB mission by supporting the application of cryo-EM in making new scientific discoveries. We provide access and training in the use ...

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveal their inner structures. It occurs during an essential step of imaging ...