The most amazing thing about cryo-EM is that it allows us to examine processes that used to be the subject of theory and speculation as we had no means to observe the motion and components ...

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveal their inner structures. It occurs during an essential step of imaging ...

Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and viruses, at near-atomic resolution.

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveal their inner structures. It occurs during an essential step of imaging ...

Additionally, cryo-EM is transforming cellular and structural biology by allowing researchers to observe the structure of proteins and biomolecular complexes in-situ within cells and tissue.

The first full-length structures of the human angiotensin-converting enzyme (ACE) have been determined by researchers from the University of Cape Town (UCT) using cryo-electron microscopy (cryo-EM).

Cryo-electron microscopy (cryo-EM) has advanced rapidly in the past few years, positioning itself as an invaluable tool for the pharmaceutical industry. Nobel Laureate Richard Henderson predicted ...

New cryo-EM images shed light on Wnt signaling Atomic-resolution pictures could eventually lead to better cancer drugs, researchers say Date: August 16, 2022 Source: UT Southwestern Medical Center ...

This protein forms amyloid structures, which researchers at Universitat Autònoma de Barcelona (Spain) have characterized using cryo-EM, advancing our understanding of the implications of amyloid ...

For instance, we have utilized cryo-ET to capture the in situ immune regulation of antimicrobial proteins through liquid-liquid phase separation (Nature 594, 424–429, 2021) and to elucidate the unique ...

Okinawa Institute of Science and Technology (OIST) Graduate University researchers have uncovered the atomic structure of the “APOBEC3G-Vif complex” using cryo-electron microscopy. Their ...