The most amazing thing about cryo-EM is that it allows us to examine processes that used to be the subject of theory and speculation as we had no means to observe the motion and components ...

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveal their inner structures. It occurs during an essential step of imaging ...

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveal their inner structures. It occurs during an essential step of imaging ...

For instance, we have utilized cryo-ET to capture the in situ immune regulation of antimicrobial proteins through liquid-liquid phase separation (Nature 594, 424–429, 2021) and to elucidate the unique ...

This protein forms amyloid structures, which researchers at Universitat Autònoma de Barcelona (Spain) have characterized using cryo-EM, advancing our understanding of the implications of amyloid ...

The first full-length structures of the human angiotensin-converting enzyme (ACE) have been determined by researchers from the University of Cape Town (UCT) using cryo-electron microscopy (cryo-EM).

Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and viruses, at near-atomic resolution.

Okinawa Institute of Science and Technology (OIST) Graduate University researchers have uncovered the atomic structure of the “APOBEC3G-Vif complex” using cryo-electron microscopy. Their ...

Cryo-electron microscopy (cryo-EM) has advanced rapidly in the past few years, positioning itself as an invaluable tool for the pharmaceutical industry. Nobel Laureate Richard Henderson predicted ...

For the first time, the structure of a DNA enzyme complex implicated in infertility and cancer has been obtained using cryo-electron microscopy (cryo-EM). A collaboration of researchers, led by ...

New cryo-EM images shed light on Wnt signaling Atomic-resolution pictures could eventually lead to better cancer drugs, researchers say Date: August 16, 2022 Source: UT Southwestern Medical Center ...