Historic, life-threatening flash flooding and landslides are expected in portions of Jamaica, southern Haiti and the Dominican Republic through the weekend, the NHC said. Peak storm surge heights could reach 9 to 13 feet above normal tide levels in Jamaica, accompanied by large and powerfully destructive waves.

Scattered and isolated showers are expected along the coast ahead of a cold front moving into South Florida Wednesday night. A coastal flood statement remains in effect for the Florida Keys through late Wednesday. Minor saltwater flooding is likely, and storm drains are likely to overflow in the area.

Heavy rains are forecast to fall further north along the U.S. East Coast later in the week, with a "marginal" risk of excessive rainfall, enough to cause isolated flash flooding, over the Appalachians and portions of the Ohio and Tennessee valleys on the evening of Oct. 29 and morning of Oct. 30.

Melissa is not expected to make landfall in Florida or the U.S. The powerful storm is expected to make landfall on the island nation of Jamaica Tuesday morning. At 8 p.m., Melissa has maximum sustained winds of 175 mph and gusts of well over 200 mph. Melissa is a dangerously powerful Category 5 hurricane.

HURRICANE MELISSA UPDATE  Melissa made a second landfall on Cuba as a Category 3 hurricane. It's continuing to bring devastating impacts⬇️

Melissa devastated Jamaica after making landfall as a deadly Category 5. The hurricane has since made landfall in Cuba. Where it's going Wednesday.