Greater than 90% depletion of B cells within 12 hours of a single dose of AAN-14xMultiple redosing of AAN-14x at desired intervals with no evidence of hepatic or other toxicityRemarkable tumor ...

From Elon Musk and Satya Nadella to the co-founder of Moderna, it’s not just tycoons in Silicon Valley who have benefited from the controversial work visa now in Donald Trump’s crosshairs, writes Io D ...

An mRNA vaccine developed by researchers from Japan suppressed abnormal blood vessel growth or neovascularization in the retina of mouse models. Neovascularization is a condition that is caused by age ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

Unlike other Codon Language Models, SynCodonLM was trained with logit-level control, masking logits for non-synonymous codons. This allowed the model to learn codon-specific patterns disentangled from ...

When Health and Human Services Secretary Robert F. Kennedy Jr. terminated $500 million in federal funding for mRNA vaccine research last week, claiming he had “reviewed the science,” his press release ...

Vaccines using mRNA technology weren’t immune to the latest round of federal research cuts. Health and Human Services Secretary Robert F. Kennedy Jr. said this week that he’s pulling the plug on ...

mRNA acts as blueprints that cells then base new proteins on. In the COVID-19 vaccines, the molecule contains instructions for a bit of the coronavirus; in the new cancer vaccine, it carries ...

A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various ...

In this valuable study, Kumar et al., provide evidence suggesting that the p130Cas drives the formation of condensates that sprout from focal adhesions to cytoplasm and suppress translation. Pending ...

The authors demonstrated the phenomenon of p130Cas, a protein primarily localized at focal adhesions, and its formation of condensates. They identified the constituents within the condensates, which ...