A child with a rare genetic disorder — spinal muscular atrophy type I — was treated prenatally for the first time. Courtesy of Jakob Owens  via Unsplash During an amniocentesis test, a long, thin ...
A修饰通过调控mRNA的翻译,影响细胞命运决定和组织结构。METTL3在调节间充质干细胞(MSCs)的成骨分化中也起着关键作用,其缺失会导致VEGFA表达下降,影响骨形成。 m?G修饰与干细胞命运 m?G修饰最初在tRNA和rRNA中被发现,近年来在mRNA的5'帽结构中也得到了鉴定。
Following the COVID-19 pandemic, mRNA-based vaccines have been shown to provide rapid and precise immune responses, however, this technology has much wider applications. Many leading pharma and ...
GSK has upgraded its longstanding alliance with CureVac on mRNA-based vaccines for respiratory infections, paying €400 million ($429 million) upfront for global rights to its influenza and COVID ...