核苷酸在人体中发挥着多种关键作用，包括参与遗传信息传递、能量代谢、细胞信号转导、调节免疫功能以及促进细胞生长和修复等。 1. 参与遗传信息传递：核苷酸是构成核酸（DNA 和 RNA）的基本单位。DNA ...

Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...

Wall Street is off to a volatile start in 2025, with investors stepping on the sell pedal after last week's jobs data, followed by a sharp about-face in sentiment following Wednesday's consumer ...

Moderna's mRNA technology gained rapid validation as sales of its covid vaccine soared in 2021 and 2022, but we think the firm has yet to secure a narrow economic moat around its business ...

But scientists at Moderna are in the late stages of testing what could be the first such shot, using mRNA technology against the virus. Here’s what to know about norovirus and where things stand ...

This modification is catalyzed by m7G methyltransferase and is widely present in various RNA molecules, including messenger RNA (mRNA), transfer RNA (tRNA), ribosomal RNA (rRNA) and microRNA (miRNA).

This manuscript provides important structural insights into the recognition and degradation of the host tRNA methyltransferase TRMT1 by SARS-CoV-2 protease nsp5 (Mpro). The data provide compelling ...

Ribo-seq（核糖体测序）是一种强大的技术，广泛应用于翻译调控机制的研究，并在疾病研究中发挥重要作用。 通过深度测序核糖体保护的mRNA片段，Ribo-seq能够捕捉特定时间和生理条件下翻译活动的快照，从而揭示基因表达调控的细节。 2、Ribo-seq 的应用领域 Ribo ...

mRNA半衰期最短，起着传递遗传信息的作用。tRNA相对分子质量最小，分子中含有10%～20%稀有碱基，包括双氢尿嘧啶，假尿嘧啶 ...