A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

Cell division is essential for the survival of all living organisms, from the simplest yeast to complex human beings.

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Two studies by researchers at the University of Konstanz investigated ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Two studies by researchers at the University of Konstanz investigated ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Quantification and characterization of these multiple HML-2 insertions in the human chromosome has been challenging due to their size, sequence homology with each other, and their repetitive nature.

Women are born with two X chromosomes and inherit one from each parent. But in every cell of their body, just one X chromosome is needed—so the other is randomly inactivated. Some cells use only ...

Get Instant Summarized Text (Gist) The completion of the final synthetic chromosome in the yeast genome marks a significant advancement in synthetic biology. This achievement enables the creation ...

Eating foods high in key nutrients, including iron, folic acid, and vitamin B12, and limiting alcohol may help increase your red blood cell count. Red blood cells are the most common cells in ...