Publishes original research, insights and opinions on evidence-based research. Focuses on the tools, methods, and concepts that are central to practising evidence-based medicine.

. Lan AJ, Colford JM Jr. The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis . Pediatrics 2000 Feb; 105 ...

Case reports and case series are uncontrolled study designs known for increased risk of bias but have profoundly influenced the medical literature and continue to advance our knowledge. In this guide, ...

Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia. Design Our study design was a ...

From promise to practice: challenges and pitfalls in the evaluation of large language models for data extraction in evidence synthesis ...

Objective This study evaluates whether Taiwan’s national oral cancer screening programme, implemented in 1999, has led to a ...

A systematic review identifies, appraises and synthesises all the empirical evidence from studies that meet prespecified eligibility criteria to answer a specific research question. As part of the ...

Introduction The concepts of evidence-based medicine are evolving as limitations of early models are addressed. In this editorial, we present a new model for evidence-based clinical decision making ...

### Summary box Access to data for drugs and vaccines has historically been fairly limited to journal article publications and hard-to-access and difficult to read regulatory reports.1 But the past ...

Key Concepts for Informed Health Choices: a framework for helping people learn how to assess treatment claims and make informed choices ...

Alcohol-based hand sanitisers, if ingested, can have toxic effects and may even be lethal. Preventable deaths from ingesting hand sanitisers have been identified. This article describes two Prevent ...

In this article we signpost readers to 10 papers we consider essential reading for anyone starting out on an evidence-based medicine journey. We have considered papers consisting a mix of old and new, ...