Hypoplastic left heart syndrome (HLHS) is a continuum which can affect all left sided cardiac structures, from the mitral valve to the aortic arch. Since Norwood’s first description of surgical ...

Sandra Terroba-Seara, Ignacio Oulego-Erroz, Daniel Palanca-Arias, Zenaida Galve-Pradel, Sara Delgado-Nicolás, Alicia Pérez-Pérez, Jorge Rodríguez-Ozcoidi, Ana Lavilla-Oíz, María Carmen Bravo, Leticia ...

Neonatal thrombocytopenia is a common clinical problem. Thrombocytopenia presenting in the first 72 hours of life is usually secondary to placental insufficiency and caused by reduced platelet ...

Background Neonatal research evaluates many different outcomes using multiple measures. This can prevent synthesis of trial results in meta-analyses, and selected outcomes may not be relevant to ...

Objective To determine if preterm birth is associated with adaptation of the hypothalamic–pituitary–adrenal (HPA) axis and whether HPA axis programming relates to the degree of prematurity (defined as ...

Introduction The management of low blood flow states in premature infants is complex. However, in the neonatal field, there remains a drive to oversimplify both the diagnosis of the condition and its ...

Jacqueline Muts, Juliette I A Lukowski, Jos W R Twisk, Anne Schoonderwoerd, Johannes B van Goudoever, Britt J van Keulen, Chris H P Van Den Akker ...

Healthcare decisions should be based on all relevant evidence.1 Usually, this is provided by randomised controlled trials (RCTs) comparing two or more interventions for a condition affecting a target ...

The changing management of haemolytic disease of the newborn is reviewed In the space of most paediatricians working lifetime, the spectrum of haemolytic disease of the newborn (HDN) has changed ...

Patient safety incidents (PSIs) occur relatively frequently in healthcare. Incident-reporting systems are designed to systematically collect information relating to PSIs in order to identify and ...

Objective To evaluate if postnatal treatment with betamethasone in extremely preterm infants was associated with neurodevelopmental impairment (NDI) at 6.5 years of age. Design Prospective cohort ...

Objective To evaluate the accuracy of neonatal MRI and general movements assessment (GMA) in predicting neurodevelopmental outcomes in infants with hypoxic-ischaemic encephalopathy (HIE). Design ...