This review discusses an approach to determining the cause of neonatal encephalopathy, as well as current evidence on resuscitation and subsequent management of hypoxic-ischaemic encephalopathy (HIE).

1 Department of Pediatrics, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA 2 Computational Genetics, Dartmouth Medical School, Lebanon, New Hampshire, USA 3 Division of Infectious ...

The management of low blood flow states in premature neonates is fraught with many challenges. We remain over-reliant on regimented stepwise protocols that use mean blood pressure as a threshold for ...

Correspondence to Dr James William Harrison Webbe, Academic Neonatal Medicine, Imperial College London, London, UK; j.webbe{at}imperial.ac.uk Background Neonatal research evaluates many different ...

Correspondence to Dr Hanneke IJsselstijn, Department of Paediatric Surgery, Erasmus MC–Sophia Children’s Hospital, Rotterdam 3015 GJ, The Netherlands; h.ijsselstijn{at}erasmusmc.nl Objectives To ...

Objective To predict length of stay in neonatal care for all admissions of very preterm singleton babies. Setting All neonatal units in England. Patients Singleton babies born at 24–31 weeks ...

Correspondence to Dr. James L Wynn, Division of Neonatology, Department of Pediatrics, University of Florida, Gainesville, FL 32611, USA; james.wynn{at}peds.ufl.edu One in 10 newborns will be born ...

Context In spontaneously breathing preterm infants with respiratory distress syndrome (RDS) receiving nasal continuous positive airway pressure, a method of less invasive surfactant administration ...

Correspondence to Dr Karen M Logan, Section of Neonatal Medicine, Chelsea and Westminster Hospital Campus, Imperial College London, London SW10 9NH, UK; k.logan{at}imperial.ac.uk Objective Maternal ...

Objective To investigate differences and calculate pooled incidence of any intraventricular haemorrhage (IVH), severe IVH (Grade III/IV, sIVH) and ventriculoperitoneal shunt (VPS) placement in preterm ...

Background Progressive ventricular dilatation after intraventricular haemorrhage (IVH) in preterm infants has a very high risk of severe disability and death. Drainage, irrigation and fibrinolytic ...

Objective Since therapeutic hypothermia became standard care for neonatal hypoxic–ischaemic encephalopathy (HIE), even fewer infants die or have disability at 18-month assessment than in the clinical ...