Background Depending on the colorectal cancer (CRC) screening programme, a colonoscopy should be performed within 1–3 months ...

Background Chronic hepatitis B virus (HBV) infection disproportionately affects people living with HIV, who are often excluded from functional cure studies. Objective This study investigates CD8+ T ...

Chronic HBV infection remains a major global health burden, with current antiviral therapies effectively suppressing viral ...

We read with great interest the article of Ratziu and colleagues, who evaluated the potential of thrombospondin-2 (TSP2), insulin-like growth factor binding protein 7, CD163 and growth differentiation ...

Background The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly increasing with high ...

Background Diffuse gastric cancer (DGC) is the most common manifestation in germline CTNNA1 variant carriers, with one study estimating a 49–57% lifetime risk by age 80. Knowledge on CTNNA1-associated ...

Recent studies have identified mucosal healing on endoscopy as a key prognostic parameter in the management of inflammatory bowel diseases (IBD), thus highlighting the role of endoscopy for monitoring ...

2 Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan 3 Department of Internal Medicine, GI Unit, Massachusetts General Hospital, Boston, Massachusetts, USA 4 ...

9 Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK Background Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency with evolving demographics and management ...

4 Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia Correspondence to Dr Hashem B El-Serag, Section of Gastroenterology and ...

Background and aims: Ulcerative colitis disease activity indices offer good statistical power but small changes in these indices may not be clinically important. There are no validated definitions of ...

Background Chronic stress is a known risk factor for cancer metastasis. However, the underlying mechanisms, particularly ...