Background Depending on the colorectal cancer (CRC) screening programme, a colonoscopy should be performed within 1–3 months ...

Objective Follow-up studies have shown that non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of incident diabetes, but currently, it is uncertain whether this risk ...

Chronic HBV infection remains a major global health burden, with current antiviral therapies effectively suppressing viral ...

Correspondence to Professor Jin-Woo Bae, Department of Life and Nanopharmaceutical Sciences and Department of Biology, Kyung Hee University, Seoul 02447, Republic of Korea; baejw{at}khu.ac.kr; ...

Objective Procedure-intense specialties, such as surgery or endoscopy, are a major contributor to the impact of the healthcare sector on the environment. We aimed to measure the amount of waste ...

The GI tract is colonised by trillions of bacteria in a complex community collectively referred to as the gut microbiota. This metabolically active ‘foreign’ body contributes to host metabolism and ...

Background and aims The crosstalk between cancer stem cells (CSCs) and their niche is required for the maintenance of stem cell-like phenotypes of CSCs. Here, we identified E26 transformation-specific ...

Objective Faecal microbiota transplantation (FMT) in germ-free (GF) mice is a common approach to study the causal role of the gut microbiota in metabolic diseases. Lack of consideration of housing ...

1 Wolfson Unit for Endoscopy and Department of Gastroenterology, St Mark’s Hospital, Harrow, UK 2 Department of Gastrointestinal Histopathology, St Mark’s Hospital, Harrow, UK Correspondence to: Dr B ...

1 Histopathology Unit, Cancer Research UK, Lincoln’s Inn Fields, London, UK 2 Histopathology Unit, Cancer Research UK, Lincoln’s Inn Fields, London, UK and Molecular Pathology Centre, Institute of ...

Background Diffuse gastric cancer (DGC) is the most common manifestation in germline CTNNA1 variant carriers, with one study estimating a 49–57% lifetime risk by age 80. Knowledge on CTNNA1-associated ...

The Center for Gastroenterological Research, Catholic University of Leuven, Leuven, Belgium Professor R Fass, University of Arizona, The Neuroenteric Clinical Research Group, Southern Arizona VA ...