The Rome diagnostic criteria for the functional bowel disorders and functional abdominal pain are used widely in research and practice. A committee consensus approach, including criticism from ...

Background and aims The gastric epithelium undergoes continuous turnover. Corpus epithelial stem cells located in the gastric isthmus serve as a source of tissue self-renewal. We recently identified ...

Correspondence to Professor Jon O Lundberg, Department of Physiology and Pharmacology, Karolinska Institutet, S-171 77 Stockholm, Sweden; jon.lundberg{at}ki.seProfessor Eddie Weitzberg, Department of ...

Background Hepatocellular carcinoma (HCC) early-stage treatment options include potentially curative surgeries. Locoregional treatments are recommended for nonsurgical intermediate stage patients, and ...

Correspondence to Professor Giovanni Targher, Endocrinology and Metabolism, University of Verona Department of Medicine, Verona 37126, Italy; giovanni.targher{at}univr.it Non-alcoholic fatty liver ...

Objective We performed a meta-analysis of observational studies to quantify the magnitude of the association between non-alcoholic fatty liver disease (NAFLD) and risk of extrahepatic cancers. Design ...

Introduction Galectin-3 is a galactoside-binding protein whose concentration is increased up to 31-fold in the bloodstream of patients with cancer including colorectal cancer. We have recently shown ...

Correspondence to Professor Shiv Kumar Sarin, Hepatology, Institute of Liver and Biliary Sciences, New Delhi, Delhi 110070, India; shivsarin{at}gmail.com Objectives Beta-blockers and endoscopic ...

Introduction There is increasing evidence for the use of probiotic bacteria in the treatment of irritable bowel syndrome (IBS). Most reports to date have been in patients with diarrhoea or bloating.

Background Existing scales for assessing faecal incontinence have not been validated against clinical assessment, or with regard to reproducibility. They also fail to take into account faecal urgency, ...

Correspondence to Mr Amyn Haji, King’s Institute of Therapeutic Endoscopy, King’s College Hospital NHS Foundation Trust, London, SE5 9RS, UK; amynhaji{at}me.com ...

Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, Arizona, USA Correspondence to: Dr K Dvorak Department of Cell Biology and Anatomy, PO Box 245044, ...