‘ Is life worth living? It all depends on the liver’ (American philosopher William James [1842—1910]) Non-alcoholic fatty liver disease (NAFLD) is currently the most frequent global liver disease.1 ...

Correspondence to Dr Daniel von Renteln, Medicine, Centre Hospitalier de L’Universite de Montreal, Montreal, Canada; danielrenteln{at}gmail.com Randomised controlled trials (RCTs) have shown that ...

Data from experimental studies have demonstrated that marine omega-3 polyunsaturated fatty acids (O3FAs) have anti-inflammatory and anticancer properties. In the last decade, large-scale randomised ...

Introduction The Covid-19 pandemic severely disrupted healthcare services. In March 2020, the government announced the ‘Everyone In’ initiative to support everyone rough sleeping or in accommodation ...

Introduction Neurodiversity (ND) encompasses diagnoses of attention deficit hyperactivity disorder (ADHD), autism spectrum disorders (ASD), dyslexia and dyspraxia. Studies describe overlap of clinical ...

Objective Exhausted hepatitis B virus (HBV)-specific CD8 T cells in chronic HBV infection are broadly heterogeneous. Characterisation of their functional impairment may allow to distinguish patients ...

Methods Short-term external funding was secured for a pilot to assess patients from primary care with suspected NAFLD and indeterminate Fib4 test in a dedicated Band 7 specialist nurse-led clinic, ...

Iron deficiency anaemia (IDA) is a major cause of morbidity and burden of disease worldwide. It can generally be diagnosed by blood testing and remedied by iron replacement therapy (IRT) using the ...

Transcription factors of the family p53 have emerged as an important set of tumour suppressors, able to regulate various cell functions like cell cycle arrest, differentiation, DNA repair, apoptosis ...

Introduction Iron deficiency anaemia (IDA) is common with BSG guidance suggesting Gastrointestinal (GI) blood loss from colonic or gastric cancer, and malabsorption in coeliac disease are the most ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

A high adenoma detection rate (ADR) is vital for effective colorectal cancer (CRC) screening, but evidence suggests limited additional benefit beyond a certain threshold. In a pooled analysis of five ...