Most colon cancers are assumed to have a premalignant adenomatous polyp phase, therefore colonoscopic detection and polypectomy provides the opportunity for cancer prevention. Some patients who have ...

Neomycin, an antibiotic which is primarily active against the aerobic gut flora and hence reduces the endogenous production of ammonia, is a well-recognised form of treatment for acute or acute on ...

Background Type 2 diabetes mellitus (T2DM) characterized by glucose intolerance accounts for approximately 90% of all diabetic patients worldwide. Although studies have monitored the gut microbiota ...

Methods As common precursors to colorectal cancer (CRC), polyps and adenomas in the large intestine may develop into malignancy over time through a cascade known as the ‘normal-polyp-adenoma-carcinoma ...

Objective We performed a meta-analysis of observational studies to quantify the magnitude of the association between non-alcoholic fatty liver disease (NAFLD) and risk of extrahepatic cancers. Design ...

Background Dental injury is an underrecognized preventable complication during endoscopy. An audit of same-day procedure cancellation in our endoscopy center showed that 43% of cases are related to ...

Data from experimental studies have demonstrated that marine omega-3 polyunsaturated fatty acids (O3FAs) have anti-inflammatory and anticancer properties. In the last decade, large-scale randomised ...

Introduction Oesophageal stenting is an important treatment option in the palliation of malignant dysphagia. There are few guidelines on choice of stents among the wide range that is available, or on ...

Lin Y, Pu S, Wang J et al. Pancreatic STAT5 activation promotes KrasG12D-induced and inflammation-induced acinar-to-ductal metaplasia and pancreatic cancer. Gut 2024;73:1831–3. A magnified version of ...

We have read with interest the recent papers of Kennedy et al 1 2 regarding the attenuated anti-SARS-CoV-2 antibody response in patients with IBD and the crucial role of the COVID-19 vaccine in this ...

Introduction Crohn’s disease (CD) is a chronic inflammatory bowel disease that can affect any part of the gastro- intestinal tract. The natural history of CD is difficult to predict. In some patients, ...

Background The gut microbiota has been implicated in immune and metabolic responses central to hepatocellular carcinoma (HCC) growth and survival. However, whether manipulating the gut microbiota ...