Heightened interest in left ventricular thrombus (LVT) stems from the consistent association of subsequent stroke and ...

Milestone articles have highlighted the frequency and types of statistical errors in research,1–5 yet fundamental errors ...

Atrial fibrillation (AF) is the most common sustained arrhythmia, currently affecting over 33 million individuals worldwide, and its prevalence is expected to more than double over the next 40 years.

Studies of the epidemiology of heart failure in the general population can inform assessments of disease burden, research, public health policy and health system care delivery. We performed a ...

Legalisation of medical and recreational cannabis commerce is spreading around the world, associated with increased use1 and ...

Introduction The clinical effectiveness of a ‘rule-out’ acute coronary syndrome (ACS) strategy for emergency department patients with chest pain, incorporating a single undetectable high-sensitivity ...

Background We aimed to characterise the variation in access to and outcomes of cardiac surgery for people in England. Methods We included people >18 years of age with hospital admission for ischaemic ...

Objective Pregnancy in women with aortic coarctation (CoA) has an estimated moderately increased risk (mWHO II–III) of adverse cardiovascular, obstetric or fetal events, but prospective data to ...

Clinical guidelines are developed by professional societies and also, in England, by an independent non-departmental public body, the National Institute for Health and Care Excellence (NICE).

Background Percutaneous coronary intervention (PCI) is frequently used for patients with chronic coronary syndrome (CCS). However, the role of PCI beyond symptom relief in CCS remains controversial.

Ventricular ectopic beats (VEBs) are commonly seen in daily clinical practice. They are largely asymptomatic but can cause upsetting symptoms in some patients. In normal hearts, their occurrence is ...

Background Anticoagulation therapy reduces stroke risk in patients with atrial fibrillation (AF), but it is often underused in older populations due to concerns about bleeding. This study aimed to ...