Adenoviruses are typically associated with mild respiratory infections, but are increasingly attributed to cardiac infection. Viruses have long been understood to infect the heart, with many studies ...

Adrenergic signaling is downregulated in various cardiac diseases, a hallmark of heart failure (HF). In classic literature, the primary cardiac β 1 adrenergic receptor (β 1 AR) undergoes ...

Canagliflozin reduced cardiovascular and kidney outcomes with no statistical evidence of heterogeneity for the treatment effect across the primary and secondary prevention subgroups in the CANVAS ...

MICROVASCULAR ALTERATIONS IN HYPERTENSION AND OBESITY The clinical importance of structural and functional alterations in the microcirculation is well established. 2 Using a micromyographic technique ...

Background Doxorubicin‐induced myocardial injury is reflected by the presence of vacuolization in both clinical and animal models. The lack of scar tissue to replace the vacuolizated cardiomyocytes ...

Gut microbiota have been associated with a wide variety of diseases, 1 with cardiometabolic diseases and their risk factors being repeatedly identified as having a microbial component. Exposure to ...

Among 71 683 patients (mean age, 70.6±9.4 years; 37.3% female; median follow-up, 23.1 months), the mean CrCl was 75.5±30.5 mL/min. The incidence of S/SE, major bleeding, ICH, and death increased ...

Abstract Inequities in stroke care and outcomes have been documented both within and among countries based on factors, such as race, geography, and socioeconomic status. Research can help us to ...

Dahl SS rats are commonly used to investigate the mechanisms contributing to SS hypertension. 1, 6, 7 They share many of the same phenotypes as at‐risk clinical populations, such as marked increases ...

A, Diagram of the ventricular action potential in the healthy heart, demonstrating the contributions of ion channels species to each phase of the ventricular action potential, including the upstroke ...

Susceptibility to atrial fibrillation (AF) is determined by well-recognized risk factors such as diabetes mellitus or hypertension, emerging risk factors such as sleep apnea or inflammation, and ...

Empaglifolzin, canagliflozin, and dapagliflozin are SGLT2 (sodium-glucose linked transporter type 2) inhibitors for treatment of type 2 diabetes mellitus that also reduce blood pressure, mortality, ...