The painkilling, antipyretic, and antiinflammatory properties of aspirin have been known for centuries. The understanding that aspirin targets cyclooxygenase-1 (COX-1) (also known as ...

Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and ...

As a therapeutic area, type 2 diabetes includes a wide range of treatment options in several mechanistic classes (although metformin has multiple classifications). One of the best therapies, ...

The planned implementation of Medicaid work requirements provides an opportunity to obtain longitudinal data to guide ...

Tobacco use kills more than 7 million people worldwide each year, including 1.3 million who die from the effects of exposure to secondhand smoke.1 As a major contributor to cancer, cardiovascular ...

Obstructive sleep apnea is one of the most common respiratory disorders worldwide. Persons with obstructive sleep apnea can have loud snoring that is detrimental to social relationships and have ...

Reductions in the estimated number of new HIV infections in the United States have overshadowed disconcerting trends among Latino people. Increased visibility, political will, and resources are needed ...

Michael Welsh, Jesús González, and Paul Negulescu have won the 2025 Lasker–DeBakey Clinical Medical Research Award for their roles in developing treatments for cystic fibrosis.

In our first Case Study in Social Medicine, a man presents to the emergency department reporting auditory hallucinations and suicidal thoughts. His case hinges on interpretations of whether his ...

Explore the current issue of The New England Journal of Medicine (Vol. 393 No. 9).

Primary care physicians have been leaving traditional practices for concierge and direct primary care practices, in which patients are offered personalized and more accessible primary care in excha ...

Enactment of the Mental Health Parity and Addiction Equity Act in 2008 improved insurance coverage for mental health and addiction treatment. Now, the Affordable Care Act could affect the financing ...