To better understand the potential health threats and underlying visual pathways of long-term light at night (LAN) exposure, we adopted a widely accepted diurnal animal model tree shrew (Tupaia ...

Many real-world systems are made of multiple interacting parts, giving rise to complex dynamical systems. A paradigm for describing such systems relies on considering high-dimensional deterministic ...

Aberrant expression of lysine-specific demethylase 1 (LSD1) has been implicated in various cancers, including acute myeloid leukemia (AML). Recent studies have revealed both catalytic and noncatalytic ...

Cellular metabolism intrinsically fuels the inflammatory function of immune cells. Itaconate is a tricarboxylic acid (TCA) cycle-derived metabolite produced from cis-aconitate by the enzyme ...

Throughout the Anthropocene controversy, it has become clear that the key to understanding the current planetary crisis is the process of acceleration of human environmental impact, which occurred on ...

The PNAS Editorial Board is made up of NAS members who are active scientists and experts in their fields. On submission, your paper is assigned to an Editorial Board member in one of the 31 NAS ...

High dust levels in West and South Asia are mainly due to strong local emission and long-distance transport (23, 24).The dust emissions are highly sensitive to local conditions such as surface winds ...

The first Global Stocktake of progress under the Paris Agreement issued a clear warning: Near-term global greenhouse gas (GHG) emissions trends are not aligned with modeled pathways consistent with ...

In the hippocampus, a region crucial for spatial and episodic learning and memory that is affected early in AD (), neural activity represents ongoing and previous experiences to support memory ...

Zhurong rover landing site and proposed shorelines in Utopia Planitia. (A) Map of Utopia Planitia, showing the landing site of the Zhurong rover and four proposed ancient shorelines (9, 11, 22, ...

The principal modus operandi of INPs is to provide a surface that strongly binds to ice, thus decreasing the free energy barrier for ice nucleation ().The strong binding is supported by the ordering ...

Emotions coordinate our behavior and physiological states during survival-salient events and pleasurable interactions. Even though we are often consciously aware of our current emotional state, such ...