DNA Helicase and Its Role in Replication, Repair, and Disease
1 天前 · UvrD helicase, for example, plays a role in nucleotide excision repair. SF1 helicases possess two RecA-like domains that facilitate ATP binding and hydrolysis, driving translocation …
DNA Helicases: Structure, Types, Functions, Examples - Microbe …
2024年10月24日 · DNA helicases are essential motor proteins that function to unwind duplex DNA to yield the transient single-stranded DNA intermediates required for replication, …
Helicase - Wikipedia
A helicase is an enzyme that plays a crucial role in the DNA replication and repair processes. Its primary function is to unwind the double-stranded DNA molecule by breaking the hydrogen …
DNA Helicases – Structure, Types, Mechanism, Functions, Examples
2024年10月24日 · DNA helicase is a crucial enzyme that plays an essential role in various cellular processes involving DNA. Its primary function is to unwind the double-stranded DNA molecule, …
Helicases: Key Players in DNA Replication, Repair, and Transcription
2024年10月17日 · Helicases are enzymes essential for maintaining genetic information integrity. These molecular motors unwind DNA and RNA strands, facilitating replication, repair, …
DNA Helicases: Key Players in Replication, Repair, and Disorders
2024年10月15日 · Explore the crucial roles of DNA helicases in genetic processes and their impact on health and disease. DNA helicases are essential enzymes that maintain genome …
DNA helicases involved in DNA repair and their roles in cancer
The RecQ and iron-sulphur (Fe-S) families of DNA helicases have prominent roles in the maintenance of genomic stability through their catalytic functions and protein interactions in …
Special Issue: DNA Helicases: Mechanisms, Biological Pathways, …
DNA helicases not only play essential roles in replication, DNA repair, and recombination, but they also influence gene expression and chromosome structure and act to resolve dynamic DNA …
Roles of DNA helicases in the maintenance of genome integrity
DNA helicases are molecular motors that in most cases use the power of ATP hydrolysis to unwind double-stranded (ds) DNA and RNA-DNA hybrids into single-stranded (ss) DNA …
DNA helicases involved in DNA repair and their roles in cancer
2013年7月11日 · Helicase-dependent DNA damage response and repair mechanisms help cells to cope with endogenous or exogenous stress to prevent chromosomal instability and maintain …