Glycosylated lysosomal membrane protein promotes tissue repair …
2025年1月22日 · Our findings highlight the crucial role of GLMP in mitigating iron overload and ferroptosis in microglia, thereby contributing to axon retention and locomotor recovery after …
Sub-cellular In-situ Characterization of Ferritin(iron) in a Rodent ...
2018年2月23日 · In this study we employ magnetic force microscopy (MFM), transmission electron microscopy (TEM), and electron energy loss spectroscopy (EELS) to characterize …
Sub-cellular In-situ Characterization of Ferritin(iron) in a …
2018年2月23日 · In this study we employ magnetic force microscopy (MFM), transmission electron microscopy (TEM), and electron energy loss spectroscopy (EELS) to characterize …
Ceruloplasmin Protects Injured Spinal Cord from Iron-Mediated …
We show that ceruloplasmin (Cp), a ferroxidase that oxidizes toxic ferrous iron, is important for this process. SCI in Cp-deficient mice demonstrates that Cp detoxifies and mobilizes iron and …
Systemic iron chelation results in limited functional and …
Excess iron accumulation within the spinal cord is thought to exacerbate tissue damage and limit functional recovery after traumatic spinal cord injury (SCI). An optimal treatment to reverse or …
Iron is essential for oligodendrocyte genesis following intraspinal ...
2009年7月1日 · Our results show that iron chelation significantly impaired TLR4-induced progenitor proliferation and new oligodendrocyte formation revealing that iron is a required …
Perls/DAB Stain for Iron - NeuroScience Associates
Perls/DAB Stain for Iron. To detect the presence of ferric iron in tissue (normally occurring or from ruptured red blood cells). The sagittal rabbit brain sections below were stained for ferric iron …
Iron Accumulation in Deep Cortical Layers Accounts for MRI
2012年4月17日 · In the spinal cord, many cells with increased CD68 immunoreactivity were found in the dorsolateral funiculus and rarely in the ventral horn. Ferritin co-localized with CD68 …
The pathology of superficial siderosis of the central nervous …
2008年8月12日 · Superficial siderosis of brain and spinal cord occurs when a bleeding source exists in the subarachnoid space. Dissemination of heme with circulating cerebrospinal fluid …
We hypothesized that TMP could exert neuroprotective effects by inhibiting ferroptosis through modulating iron metabolism, but its mechanism is unclear. Through in vivo and in vitro …