Here we dissect the etiology and pathology at specific stages: (i) triggering, (ii) maturation, (iii) targeting, and (iv) fulminant stage, concomitant with hyperplastic synovium, cartilage damage, bone erosion, and systemic consequences.

2019年11月9日 · Summarize the pathophysiology of rheumatoid arthritis. Outline the use of rheumatoid factor and anti-citrullinated protein antibodies in evaluating rheumatoid arthritis. Review the importance of improving care coordination among the interprofessional team to improve outcomes for those affected with rheumatoid arthritis.

2018年4月27日 · Here we dissect the etiology and pathology at specific stages: (i) triggering, (ii) maturation, (iii) targeting, and (iv) fulminant stage, concomitant with hyperplastic synovium, cartilage...

Rheumatoid arthritis is best characterized as an immune mediated inflammatory disease (IMID). Within a framework that recognizes both immunological activation and inflammatory pathways, we can begin to evaluate the multiple components of disease initiation and propagation.

Rheumatoid arthritis (RA) is a chronic inflammatory and autoimmune disease with multisystem involvement, including genetic, epigenetic, metabolic, and immune factors. This review focuses on the importance of recently identified epigenetic and metabolic risk factors for immune dysfunction and pathogenic tissue‐remodeling programs in RA ...

2023年6月1日 · Recent advancements in technology and science thoroughly changed the basic understanding and treatment approach of rheumatoid arthritis (RA). RA is a chronic inflammatory autoimmune disease characterized by progressive inflammation, bone and cartilage destruction, resulting in progressive disability, reduced lifespan and increased death rates.

2024年6月20日 · Rheumatoid arthritis (RA), classified as an autoimmune disease, is a chronic inflammatory condition characterized by joint swelling and tenderness, along with the progressive erosion of synovial joints; these symptoms often lead to significant disability and an increased risk of premature mortality (Ann Rheum Dis 2010;69:1580)

2018年2月8日 · Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease that primarily affects the joints and is associated with autoantibodies that target various molecules including...

Rheumatoid arthritis (RA) is currently diagnosed and treated when an individual presents to health care with signs and symptoms of inflammatory arthritis (IA) as well as other features such as autoantibodies and/or imaging findings that provide sufficient confidence that the individual has RA-like IA (e.g. meeting established classification ...

2018年4月27日 · Here we dissect the etiology and pathology at specific stages: (i) triggering, (ii) maturation, (iii) targeting, and (iv) fulminant stage, concomitant with hyperplastic synovium, cartilage damage, bone erosion, and systemic consequences.